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Article

Distinct DNA methylation targets by aging and chronic inflammation: a pilot study using gastric mucosa infected with Helicobacter pylori.

Clinical epigenetics - 11 Dec 2019

Yamashita Satoshi, Nanjo Sohachi, Rehnberg Emil, Iida Naoko, Takeshima Hideyuki, Ando Takayuki, Maekita Takao, Sugiyama Toshiro, Ushijima Toshikazu

Abstract excerpt

BACKGROUND: Aberrant DNA methylation is induced by aging and chronic inflammation in normal tissues. The induction by inflammation is widely recognized as acceleration of age-related methylation. However, few studies addressed target genomic regions and the responsible factors in a genome-wide manner. Here, we analyzed methylation targets by aging and inflammation, taking advantage of the potent methylation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31829249
DOI: 10.1186/s13148-019-0789-8
PMCID: PMC6907118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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