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Article

Mucinous adenocarcinoma is a pharmacogenomically distinct subtype of colorectal cancer.

The pharmacogenomics journal - 1 Jun 2020

Reynolds Ian S, O'Connell Emer, Fichtner Michael, McNamara Deborah A, Kay Elaine W, Prehn Jochen H M, Furney Simon J, Burke John P

Abstract excerpt

Mucinous colorectal cancer is a unique histological subtype that is known to respond poorly to cytotoxic chemotherapy and radiotherapy. There are a number of genes known to be associated with resistance to 5-fluorouracil (5-FU), oxaliplatin, and irinotecan. The aim of this study was to compare the somatic mutation frequency and copy number variation (CNV) in these genes between mucinous and non-mucinous...

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Source

Identifiers

PMID: 31819162
DOI: 10.1038/s41397-019-0137-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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