Article
Gene Variant in the NF-κB Pathway Inhibitor NFKBIA Distinguishes Patients with Psoriatic Arthritis within the Spectrum of Psoriatic Disease.
BioMed research international - 1 Jan 2019
Coto-Segura Pablo, Coto Eliecer, González-Lara Leire, Alonso Belén, Gómez Juan, Cuesta-Llavona Elías, Queiro Rubén
Abstract excerpt
BACKGROUND AND AIMS: The NF-κB pathway has been implicated in the genetic aetiology of psoriatic disease. However, since most patients with arthritis have psoriasis, discerning the genetic contributions to both aspects of psoriatic disease is not easy. Our aim was to study the association of common polymorphisms in genes of the NF-κB pathway in patients with psoriatic disease in order to dissect the contribution...
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