Article
New insights into the pathogenesis and genetics of psoriatic arthritis.
Nature clinical practice. Rheumatology - 1 Feb 2009
Nograles Kristine E, Brasington Richard D, Bowcock Anne M
Abstract excerpt
Psoriasis vulgaris and psoriatic arthritis (PsA) are inter-related heritable diseases. Psoriatic skin is characterized by hyperproliferative, poorly differentiated keratinocytes and severe inflammation. Psoriatic joints are characterized by highly inflamed synovia and entheses with focal erosions of cartilage and bone. Genetic analyses have uncovered risk factors shared by both psoriasis and PsA. Predisposition...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
