Article
Molecular characterization of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates identifies local transmission of infection in Kuwait, a country with a low incidence of TB and MDR-TB.
European journal of medical research - 5 Dec 2019
Al-Mutairi Noura M, Ahmad Suhail, Mokaddas Eiman M
Abstract excerpt
BACKGROUND: Increasing incidence of multidrug-resistant Mycobacterium tuberculosis infections is hampering global tuberculosis control efforts. Kuwait is a low-tuberculosis-incidence country, and ~ 1% of M. tuberculosis strains are resistant to rifampicin and isoniazid (MDR-TB). This study detected mutations in seven genes predicting resistance to rifampicin, isoniazid, pyrazinamide, ethambutol and streptomycin...
Topics
- Antitubercular Agents
- Bacterial Proteins
- Drug Resistance, Multiple, Bacterial
- Female
- Follow-Up Studies
- Genotype
- Humans
- Incidence
- Kuwait
- Male
- Mutation