Article
Characterization of Mycobacterium tuberculosis genotypes and their correlation to multidrug resistance in Lusaka, Zambia.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jan 2021
Solo Eddie Samuneti, Suzuki Yasuhiko, Kaile Trevor, Bwalya Precious, Lungu Patrick, Chizimu Joseph Yamweka, Shah Yogendra, Nakajima Chie
Abstract excerpt
OBJECTIVES: The burden of multidrug-resistant tuberculosis (MDR-TB) has been reported to be increasing in Zambia. The reasons for the increase are still unclear. This study determined the diversity of Mycobacterium tuberculosis genotypes among isolates in Lusaka, the capital city, and investigated their association with MDR-TB. METHODS: Spoligotyping, large sequence polymorphism (LSP) analysis, and sequencing of...
Topics
- Antitubercular Agents
- Drug Resistance, Multiple, Bacterial
- Genetic Variation
- Genotype
- Hospitals, Teaching
- Humans
- Mutation
- Phenotype
- Polymorphism, Genetic
- Tuberculosis, Multidrug-Resistant
- Zambia