Article
Bayesian semi-nonnegative matrix tri-factorization to identify pathways associated with cancer phenotypes.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2020
Park Sunho, Kar Nabhonil, Cheong Jae-Ho, Hwang Tae Hyun
Abstract excerpt
Accurate identification of pathways associated with cancer phenotypes (e.g., cancer subtypes and treatment outcomes) could lead to discovering reliable prognostic and/or predictive biomarkers for better patients stratification and treatment guidance. In our previous work, we have shown that non-negative matrix tri-factorization (NMTF) can be successfully applied to identify pathways associated with specific...
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