Protective Effects of HLA-DRB1*08:03 and HLA-DQA1*01:03 Alleles for Alloanti-D Immunisation in the Southern Chinese D-Negative Pregnant Women.

doi:10.1111/tan.70434

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Article

Protective Effects of HLA-DRB108:03 and HLA-DQA101:03 Alleles for Alloanti-D Immunisation in the Southern Chinese D-Negative Pregnant Women.

HLA - 1 Oct 2025

Wen Jizhi, Ma Xiaojie, Wang Zhen, Ding Haoqiang, Wei Ling, Jia Shuangshuang

Abstract excerpt

Alloanti-D is still one of the most common causes of severe hemolytic disease of the fetus and newborn in China, as rhesus immunoglobulin (RhIG) prophylaxis is not a routine practice throughout China. HLA plays an important role in the susceptibility to alloimmunisation against red blood cell antigens. This study was designed to identify susceptible and protective HLA alleles for alloanti-D immunisation after...

Read the complete abstract on PubMed

Topics

Humans
Female
Pregnancy
HLA-DRB1 Chains
Alleles
HLA-DQ alpha-Chains
Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

China

Gene Frequency

Isoantibodies

Genotype

Rho(D) Immune Globulin

Rh-Hr Blood-Group System

East Asian People

Source

Open in PubMed

Identifiers

PMID: 41133947
DOI: 10.1111/tan.70434

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