Article
Low frequency of mutation of epidermal growth factor receptor (EGFR) and arrangement of anaplastic lymphoma kinase (ALK) in primary pulmonary lymphoepithelioma-like carcinoma.
Thoracic cancer - 1 Feb 2020
Yin Kai, Feng Hui-Bo, Li Lin-Lin, Chen Yu, Xie Zhi, Lv Zhi-Yi, Guo Wei-Bang, Lu Dan-Xia, Yang Xue-Ning, Yan Wen-Qing, Wu Yi-Long, Zhang Xu-Chao
Abstract excerpt
BACKGROUND: Primary pulmonary lymphoepithelioma-like carcinoma (PLELC) is a rare and unique subtype of lung cancer. However, the prevalence of driver alterations, such as epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements, and the response of tyrosine kinase inhibitor (TKIs) in PLELC has not been thoroughly investigated. METHOD: We retrospectively reviewed the...
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