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Article

Two different patterns of lung adenocarcinoma with concomitant EGFR mutation and ALK rearrangement.

Tumori - 1 Feb 2022

Zhao Dashi, Fan Jun, Peng Li, Huang Bo, Zhu Yili, Shi Heshui, Dai Xiaofang, Nie Xiu

Abstract excerpt

Epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements are considered mutually exclusive in non-small cell lung cancer (NSCLC), especially in lung adenocarcinoma (LUAC). However, sporadic cases harboring concomitant EGFR and ALK alterations have been increasingly reported. There is no consensus opinion regarding the treatment of patients positive for both molecular...

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Identifiers

PMID: 33818198
DOI: 10.1177/03008916211005546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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