Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review.

The British journal of dermatology - 1 Sept 2020

Blakeway H, Van-de-Velde V, Allen V B, Kravvas G, Palla L, Page M J, Flohr C, Weller R B, Irvine A D, McPherson T, Roberts A, Williams H C, Reynolds N, Brown S J, Paternoster L, Langan S M

Abstract excerpt

BACKGROUND: Epidemiological studies indicate that gene-environment interactions play a role in atopic dermatitis (AD). OBJECTIVES: To review the evidence for gene-environment interactions in AD aetiology, focusing on filaggrin (FLG) loss-of-function mutations. METHODS: A systematic search from inception to September 2018 in Embase, MEDLINE and BIOSIS was performed. Search terms included all synonyms for AD and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cats
Share to Dermatitis, Atopic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Environmental Exposure

Share to Filaggrin Proteins

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Intermediate Filament Proteins

Share to Loss of Function Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 31794059
DOI: 10.1111/bjd.18778
PMCID: PMC7496176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review.PMID 31794059Read ↗

Genetics of Atopic Dermatitis: From DNA Sequence to Clinical RelevanceSemantic proximity Read ↗

Genetic/Environmental Contributions and Immune Dysregulation in Children with Atopic DermatitisSemantic proximity Read ↗

The Genetics and Epigenetics of Atopic Dermatitis-Filaggrin and Other Polymorphisms.Semantic proximity Read ↗

Study of Genetic Mutations and Their Association With the Development of Atopic Dermatitis and Other Skin Diseases.Semantic proximity Read ↗

Increased loss-of-function filaggrin gene mutation prevalence in atopic dermatitis patients across northern latitudes indicates genetic fitness: A systematic review and meta-analysis.Semantic proximity Read ↗

The effect of phthalate exposure and filaggrin gene variants on atopic dermatitisSemantic proximity Read ↗

Genetics in Atopic Dermatitis: Historical Perspective and Future Prospects.Semantic proximity Read ↗

Genetics of atopic dermatitis.Semantic proximity Read ↗

The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study.Semantic proximity Read ↗

Loss-of-function mutations within the filaggrin gene and atopic dermatitis.Semantic proximity Read ↗

Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis.Semantic proximity Read ↗

Inflammation-related proteins in blood after dermal exposure to some common chemicals depend on the skin barrier gene filaggrin - a human experimental study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.