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Article

Generation of MR1-Restricted T Cell Clones by Limiting Dilution Cloning of MR1 Tetramer+ Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020

Cansler Meghan, Null Megan, Meermeier Erin, Swarbrick Gwendolyn, Lewinsohn David, Harriff Melanie

Abstract excerpt

Tetramers are a powerful tool for identification of T cell subsets that are restricted by specific antigen presenting molecules and their cognate antigens. The generation of T cell clones from specific T cell subsets allows for further investigation of the phenotype and function of these cells. Here, we describe a method for sorting and cloning of MR1-restricted T cells using the MR1/5-OP-RU tetramer. This...

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Identifiers

PMID: 31792826
DOI: 10.1007/978-1-0716-0207-2_15
PMCID: PMC7063788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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