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Purification, Phenotypic and Functional Analyses of Regulatory T Cells in Autoimmunity.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

Shah Nainisha, Fortuin Annemarie, Afonso Georgia, Louis-Plence Pascale

Abstract excerpt

Regulatory T cells (Tregs) are essential in maintaining immune tolerance and preventing autoimmune responses. In this chapter, we describe methods for isolating highly purified human CD4+ Tregs from peripheral blood mononuclear cells and synovial fluid mononuclear cells of patients with rheumatoid arthritis, as an example of autoimmune disease. We outline the methods for flow cytometry-based cell sorting to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41269546
DOI: 10.1007/978-1-0716-4997-8_3

Genes

CD4

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