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Article

Oncogenic Drivers and Development.

Cancer discovery - 1 Dec 2019

Cruz Hernandez David, Vyas Paresh

Abstract excerpt

In this issue of Cancer Discovery, Lopez and colleagues show that the aggressive acute leukemic phenotype caused by the chimeric transcription factor CBFA2T3-GLIS2 varies depending on the developmental stage of the cell transformed (i.e., fetal vs. adult). This is likely a general principle in pediatric cancers and begins to explain why some cancer phenotypes are more common in infants and young children, whereas...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 31792123
DOI: 10.1158/2159-8290.CD-19-1082

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