Article
MIF -173G/C polymorphism is associated with NMO disease severity.
Journal of neuroimmunology - 15 Feb 2020
Brill Livnat, Vaknin-Dembinsky Adi, Zveik Omri, Haham Nitsan, Miller Keren, Benedek Gil
Abstract excerpt
Our knowledge about genetic factors that drive the worsening of neuromyelitis optica (NMO) is limited. Herein, we analyzed the macrophage migration inhibitory factor (MIF) -173G/C functional polymorphism in NMO patients and controls. Our data reveal that the frequency of the high-expression MIF genotypes (CC/GC) did not differ between the two groups. However, frequency of this genotypes was elevated in patients...
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