Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Correlation of AQP4 gene polymorphism with NMO clinical phenotypes and its underlying mechanism].

Zhonghua yi xue za zhi - 17 Feb 2015

Qiu Wei, Chang Yanyu, Li Rui, Long Youming, Huang Jianhua, Mai Weihua, Sun Xiaobo, Lu Zhengqi, Hu Xueqiang

Abstract excerpt

OBJECTIVE: To explore the correlation between aquaporin-4 (AQP4) gene single nucleotide polymorphism (SNP) and clinical phenotypes of neuromyelitis optica (NMO) and its underlying mechanism. METHODS: Eight SNPs in AQP4 gene regulatory region were selected and genotyped for 208 anti-AQP4 autoantibodies (NMO-IgG) seropositive cases during January 2010 to January 2014 and 204 healthy subjects. Then the correlation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aquaporin 4
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to AQP4 gene

Share to Genotype

Share to MicroRNAs

Share to Neuromyelitis Optica

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25916924

Genes

AQP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Correlation of AQP4 gene polymorphism with NMO clinical phenotypes and its underlying mechanism].PMID 25916924Read ↗

Human aquaporin 4 gene polymorphisms in Chinese patients with neuromyelitis optica.Semantic proximity Read ↗

Genetic analysis of the aquaporin-4 gene for anti-AQP4 antibody-positive neuromyelitis optica in a Japanese population.Semantic proximity Read ↗

Association Between the Single Nucleotide Polymorphism and the Level of Aquaporin-4 Protein Expression in Han and Minority Chinese with Inflammatory Demyelinating Diseases of the Central Nervous System.Semantic proximity Read ↗

Significant Association Between Fc Receptor-Like 3 Polymorphisms (-1901A>G and -658C>T) and Neuromyelitis Optica (NMO) Susceptibility in the Chinese Population.Semantic proximity Read ↗

Genetic factors for susceptibility to and manifestations of neuromyelitis optica.Semantic proximity Read ↗

Epidemiological, clinical and immunological aspects of neuromyelitis optica (NMO).Semantic proximity Read ↗

Comparisons of clinical phenotype, radiological and laboratory features, and therapy of neuromyelitis optica spectrum disorder by regions: update and challenges.Semantic proximity Read ↗

Clinical features of neuromyelitis optica in a large Japanese cohort: comparison between phenotypes.Semantic proximity Read ↗

A Comprehensive Review on the Role of Genetic Factors in Neuromyelitis Optica Spectrum Disorder.Semantic proximity Read ↗

Neuromyelitis optica (NMO)--an autoimmune disease of the central nervous system (CNS).Semantic proximity Read ↗

Genetic analysis of aquaporin-4 in neuromyelitis optica.Semantic proximity Read ↗

IRAK1 polymorphisms are associated with susceptibility to neuromyelitis optica spectrum disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.