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Article

Frequent GNAS and KRAS mutations in pyloric gland adenoma of the stomach and duodenum.

The Journal of pathology - 1 Mar 2013

Matsubara Akiko, Sekine Shigeki, Kushima Ryoji, Ogawa Reiko, Taniguchi Hirokazu, Tsuda Hitoshi, Kanai Yae

Abstract excerpt

Gastric and duodenal adenomas exhibit a significant morphological and phenotypical diversity and are classified into intestinal-type, foveolar-type and pyloric gland adenomas. We analysed the mutations in GNAS, KRAS, BRAF and CTNNB1 and the expressions of mismatch repair (MMR) proteins in 80 gastric and 32 duodenal adenomas with histologically distinct subtypes, as well as in 71 gastric adenocarcinomas....

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Source

Identifiers

PMID: 23208952
DOI: 10.1002/path.4153

Genes

GNAS
KRAS
BRAF
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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