Article
Childhood intelligence attenuates the association between biological ageing and health outcomes in later life.
Translational psychiatry - 28 Nov 2019
Stevenson Anna J, McCartney Daniel L, Hillary Robert F, Redmond Paul, Taylor Adele M, Zhang Qian, McRae Allan F, Spires-Jones Tara L, McIntosh Andrew M, Deary Ian J, Marioni Riccardo E
Abstract excerpt
The identification of biomarkers that discriminate individual ageing trajectories is a principal target of ageing research. Some of the most promising predictors of biological ageing have been developed using DNA methylation. One recent candidate, which tracks age-related phenotypes in addition to chronological age, is 'DNAm PhenoAge'. Here, we performed a phenome-wide association analysis of this biomarker in a...
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