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Astrovirus Replication Is Inhibited by Nitazoxanide In Vitro and In Vivo

28 Nov 2019

Abstract excerpt

Human astroviruses (HAstV) are thought to cause between 2 and 9% of acute, nonbacterial diarrhea cases in children worldwide. HAstV infection can be especially problematic in immunocompromised people and infants, where the virus has been associated with necrotizing enterocolitis and severe and persistent diarrhea, as well as rare instances of systemic and fatal disease. And yet, no antivirals have been identified...

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PMID: 31776285
DOI: 10.1128/jvi.01706-19

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