Article
Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study.
Acta oncologica (Stockholm, Sweden) - 1 Mar 2020
Mezheyeuski Artur, Ponten Fredrik, Edqvist Per-Henrik, Sundström Magnus, Thunberg Ulf, Qvortrup Camilla, Pfeiffer Per, Sorbye Halfdan, Glimelius Bengt, Dragomir Anca
Abstract excerpt
Background: Survival and response to therapy in patients with metastatic colorectal cancer (mCRC) are very heterogeneous. There is an unmet need for better markers of prognosis and treatment benefit for mCRC patients. The homeobox 2 gene SATB2 has a highly specific expression in colorectal tissue and is associated with better prognosis in non-metastatic CRC.Material and methods: A population-based cohort of 798...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
