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Article

Loss of SATB2 Expression in Colorectal Carcinoma Is Associated With DNA Mismatch Repair Protein Deficiency and BRAF Mutation.

The American journal of surgical pathology - 1 Oct 2018

Ma Changqing, Olevian Dane C, Lowenthal Brett M, Jayachandran Priya, Kozak Margaret M, Chang Daniel T, Pai Reetesh K

Abstract excerpt

The special AT-rich sequence binding protein (SATB2) has been reported to be a specific immunohistochemical marker for colorectal carcinoma; however, correlation of SATB2 expression with molecular alterations commonly assessed in colorectal carcinoma has not been performed. We examined the immunohistochemical expression of SATB2 in 586 adenocarcinomas of the gastrointestinal (GI) tract and pancreas to assess its...

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Topics

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Matrix Attachment Region Binding Proteins

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 30001238
DOI: 10.1097/PAS.0000000000001116

Genes

SATB2
CDX2
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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