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Article

Maya gene variants related to the risk of type 2 diabetes in a family-based association study.

Gene - 10 Mar 2020

Domínguez-Cruz Miriam G, Muñoz María de Lourdes, Totomoch-Serra Armando, García-Escalante María G, Burgueño Juan, Valadez-González Nina, Pinto-Escalante Doris, Díaz-Badillo Alvaro

Abstract excerpt

Mexican Maya populations have a notably high prevalence of type 2 diabetes (T2D) as a consequence of the interaction between environmental factors and a genetic component. To assess the impact of 24 single nucleotide variants (SNVs) located in 18 T2D risk genes, we conducted a family-based association evaluation in samples from Maya communities with a high incidence of the disease. A total of four hundred...

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PMID: 31759989
DOI: 10.1016/j.gene.2019.144259

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