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Whole-exome sequencing in maya indigenous families: variant in PPP1R3A is associated with type 2 diabetes.

Molecular genetics and genomics : MGG - 1 Oct 2018

Sánchez-Pozos Katy, Ortíz-López María Guadalupe, Peña-Espinoza Bárbara I, de Los Ángeles Granados-Silvestre María, Jiménez-Jacinto Verónica, Verleyen Jérôme, Tekola-Ayele Fasil, Sanchez-Flores Alejandro, Menjivar Marta

Abstract excerpt

It has been presumed that increased susceptibility in Mexicans to type 2 diabetes (T2D) is attributed to the Native American genetic ancestry. Nonetheless, it is not known if there are private genetic variants that confer susceptibility to develop T2D in our population. The Maya indigenous group has the highest proportion of Native American ancestry (98%) which makes it a representative group of the original...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29948331
DOI: 10.1007/s00438-018-1453-2

Genes

APOB
TPPP2

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