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Article

Increased CD8 Tumor Infiltrating Lymphocytes in Colorectal Cancer Microenvironment Supports an Adaptive Immune Resistance Mechanism of PD-L1 Expression.

Asian Pacific journal of cancer prevention : APJCP - 1 Nov 2019

Sudoyo Aru W, Kurniawan Antonius N, Kusumo Gita D, Putra Teguh P, Rexana Fritzie A, Yunus Muhammad, Budiyati Akterono D, Kurniawan Dicky, Utama Andi, Utomo Ahmad R

Abstract excerpt

BACKGROUND: Tumor cells express programmed death ligand-1 (PD-L1) through several biological processes, thereby having different clinical significance depending on the underlying mechanism of expression. Currently, mechanisms leading to PDL1 gene expression in colorectal cancer (CRC) are not fully understood. METHODS: We investigated 98 Indonesia CRC patients to determine PD-L1 protein expressions and their...

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Identifiers

PMID: 31759368
DOI: 10.31557/APJCP.2019.20.11.3421
PMCID: PMC7063011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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