Article
Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors.
Molecular cancer - 23 Aug 2018
Yi Ming, Jiao Dechao, Xu Hanxiao, Liu Qian, Zhao Weiheng, Han Xinwei, Wu Kongming
Abstract excerpt
Programmed cell death protein 1/programmed cell death ligand 1 (PD-1/PD-L1) is a negative modulatory signaling pathway for activation of T cell. It is acknowledged that PD-1/PD-L1 axis plays a crucial role in the progression of tumor by altering status of immune surveillance. As one of the most promising immune therapy strategies, PD-1/PD-L1 inhibitor is a breakthrough for the therapy of some refractory tumors....
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