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Article

The Antimicrobial and Immunomodulatory Function of RNase 7 in Skin

4 Nov 2019

Abstract excerpt

The human ribonuclease RNase 7 has been originally isolated from human skin and is a member of the human RNase A superfamily. RNase 7 is constantly released by keratinocytes and accumulates on the skin surface. The expression of RNase 7 in keratinocytes can be induced by diverse stimuli such as cytokines, growth factors, and microbial factors. RNase 7 exhibits a potent broad spectrum of antimicrobial activity...

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Identifiers

PMID: 31749808
DOI: 10.3389/fimmu.2019.02553

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