Article

The antimicrobial protein RNase 7 directly restricts herpes simplex virus infection of human keratinocytes

2024-07-16

Abstract excerpt

Approximately 22% of moderately to severely affected atopic dermatitis (AD) patients have a history of eczema herpeticum, a disseminated rash primarily caused by herpes simplex virus type 1 (HSV-1). Reduced activity of antimicrobial peptides may contribute to the increased susceptibility of AD patients to HSV-1. We previously demonstrated that the antimicrobial protein RNase 7 promotes self-DNA sensing by human ke...

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Literature Corpus work: 3a15b030-a413-5eca-984a-7ee73b9cc843
DOI: 10.22541/au.172115210.03179534/v1

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