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Article

Cost-Effectiveness of Personalized Screening for Colorectal Cancer Based on Polygenic Risk and Family History.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2020

Cenin Dayna R, Naber Steffie K, de Weerdt Anne C, Jenkins Mark A, Preen David B, Ee Hooi C, O'Leary Peter C, Lansdorp-Vogelaar Iris

Abstract excerpt

BACKGROUND: There is growing evidence for personalizing colorectal cancer screening based on risk factors. We compared the cost-effectiveness of personalized colorectal cancer screening based on polygenic risk and family history to uniform screening. METHODS: Using the MISCAN-Colon model, we simulated a cohort of 100 million 40-year-olds, offering them uniform or personalized screening. Individuals were...

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Identifiers

PMID: 31748260
DOI: 10.1158/1055-9965.EPI-18-1123
PMCID: PMC7159991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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