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Article

Genotype-phenotype associations in hereditary spastic paraplegia: a systematic review and meta-analysis on 13,570 patients.

Journal of neurology - 1 Jun 2021

Erfanian Omidvar Maryam, Torkamandi Shahram, Rezaei Somaye, Alipoor Behnam, Omrani Mir Davood, Darvish Hossein, Ghaedi Hamid

Abstract excerpt

AIMS: The hereditary spastic paraplegias (HSPs) are a heterogeneous group of inherited neurodegenerative disorders. Although, several genotype-phenotype studies have carried out on HSPs, the association between genotypes and clinical phenotypes remain incomplete since most studies are small in size or restricted to a few genes. Accordingly, this study provides the systematic meta-analysis of genotype-phenotype...

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Source

Identifiers

PMID: 31745725
DOI: 10.1007/s00415-019-09633-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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