Article
Genetic Distribution of the LTA +252 A>G and TNFA -308 G > A Polymorphisms in the Moroccan Population.
Genetic testing and molecular biomarkers - 1 Dec 2019
Aznag Fatima Zahra, Moutaoufik Mohamed Taha, Korrida Amal, Izaabel El Hassan
Abstract excerpt
Introduction: The LTA and TNFA genes encode key proinflammatory cytokines with diverse activities in the immune responses. Single nucleotide polymorphisms (SNPs) in the LTA rs909253 (+252 A > G) and TNFA rs1800629 (-308 G > A) genes have been associated with susceptibility to many complex diseases. The aim of this study was to assess the frequency for these two key polymorphisms in the Moroccan population....
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