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Article

Quenching the quorum sensing system: potential antibacterial drug targets

27 Jan 2011

Abstract excerpt

Emergence of antibiotic and multi-drug resistant pathogenic bacteria has created the need for new drugs and drug targets. During pathogenesis bacteria release signals which regulate virulence and pathogenicity related genes. Such bacteria co-ordinate their virulent behaviour in a cell density dependent phenomenon termed as quorum sensing (QS). In contrast, microbes interfere with QS system by quenching the...

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Share to Antimicrobial Resistance in Staphylococcus
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PMID: 21271798
DOI: 10.3109/1040841x.2010.532479

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