Article
Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study.
Diabetologia - 1 Feb 2020
Mattila Markus, Erlund Iris, Lee Hye-Seung, Niinistö Sari, Uusitalo Ulla, Andrén Aronsson Carin, Hummel Sandra, Parikh Hemang, Rich Stephen S, Hagopian William, Toppari Jorma, Lernmark Åke, Ziegler Anette G, Rewers Marian, Krischer Jeffrey P, Norris Jill M, Virtanen Suvi M
Abstract excerpt
AIMS/HYPOTHESIS: We studied the association of plasma ascorbic acid with the risk of developing islet autoimmunity and type 1 diabetes and examined whether SNPs in vitamin C transport genes modify these associations. Furthermore, we aimed to determine whether the SNPs themselves are associated with the risk of islet autoimmunity or type 1 diabetes. METHODS: We used a risk set sampled nested case-control design...
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