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Article

Proof-of-concept study of a multi-gene risk score in adolescent bipolar disorder.

Journal of affective disorders - 1 Feb 2020

Dimick Mikaela K, Cazes Jaime, Fiksenbaum Lisa M, Zai Clement C, Tampakeras Maria, Freeman Natalie, Youngstrom Eric A, Kennedy James L, Goldstein Benjamin I

Abstract excerpt

BACKGROUND: Few studies have examined multiple genetic variants concurrently for the purpose of classifying bipolar disorder (BD); the literature among youth is particularly sparse. We selected 35 genetic variants, previously implicated in BD or associated characteristics, from which to identify the most robustly predictive group of genes. METHODS: 215 Caucasian adolescents (114 BD and 101 healthy controls (HC),...

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Identifiers

PMID: 31727397
DOI: 10.1016/j.jad.2019.11.009

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