Article
Association of miR-155 and Angiotensin Receptor Type 1 Polymorphisms with the Risk of Ischemic Stroke in a Chinese Population.
DNA and cell biology - 1 Jan 2020
Li You, Peng Yaoqun, Yao Shaoyu, Chen Linfa, Li Shengnan, Wang Mengxu, Chen Shaofeng, Chen Xinglan, Deng Fu, Hu Weidong, Zhu Peiyi, Zhao Bin, Zhong Wangtao, Ma Guoda
Abstract excerpt
There is increasing evidence suggesting that dysregulation of miR-155 and its target angiotensin receptor type 1 (AT1R) are linked to the incidence of ischemic stroke (IS), but the underlying mechanisms remain to be clarified. In this study, we therefore sought to investigate how miR-155 and AT1R polymorphisms affect IS risk. We included 579 IS patients and 509 age-matched controls in the present analysis,...
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