Article
Association of the genetic polymorphisms in pre-microRNAs with risk of ischemic stroke in a Chinese population.
PloS one - 1 Jan 2015
Huang Suli, Zhou Shiquan, Zhang Yanwei, Lv Ziquan, Li Shanshan, Xie Changhui, Ke Yuebin, Deng Pingjian, Geng Yijie, Zhang Qian, Chu Xiaofan, Yi Zhaohui, Zhang Ying, Wu Tangchun, Cheng Jinquan
Abstract excerpt
microRNA (miRNA) plays a role in the pathogenesis of ischemic stroke, and single nucleotide polymorphisms in miRNA genes may contribute to disease susceptibility. However, the effect of miR-146a, miR-196a2, and miR-499 polymorphisms on ischemic stroke susceptibility has been rarely reported. Using the TaqMan assay, we evaluated the association of hsa-miR-146a/rs2910164, hsa-miR-196a2/rs11614913, and...
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