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Article

Impact of miR-200b and miR-495 variants on the risk of large-artery atherosclerosis stroke.

Metabolic brain disease - 1 Feb 2023

Qin Shanmei, Shen Chong, Tang Wuzhuang, Wang Mengmeng, Lin Ying, Wang Zhaojun, Li Yunzi, Zhang Zhizhong, Liu Xinfeng

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) of microRNAs (miRNAs) may alter miRNA transcription, maturation and target specificity, thus affecting stroke susceptibility. We aimed to investigate whether miR-200b and miR-495 SNPs may be associated with ischemic stroke (IS) risk and further explore underlying mechanisms including related genes and pathways. MiR-200b rs7549819 and miR-495 rs2281611 polymorphisms were...

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PMID: 36374407
DOI: 10.1007/s11011-022-01119-w

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