Article
Association of cyclin-dependent kinase inhibitor 2A/B with increased risk of developing breast cancer.
Journal of cellular physiology - 1 Jun 2020
Seifi Sima, Pouya Farzaneh, Rahmani Mahsa, Mehramiz Mehrane, Rastgar-Moghadam Azam, Gharib Masoumeh, Rahmani Farzad, Shahidsales Soodabeh, Hassanian Seyed Mahdi, Khazaei Majid, Dadjoo Parisa, Parvin Seyede Sara, Yazdinezhad Yeganeh, Parizadeh Seyed Mohammad Reza, Ferns Gordon A, Fathi Mehdi, Avan Amir
Abstract excerpt
There is a growing body of data reporting the association of genetic alterations in chromosome 9P21 with the risk of developing cancer. In the current study, we studied the association of a genetic variant in CDKN2A/B, rs1333049, with the risk of developing breast cancer. A total of 339 participants with and without breast cancer entered to the study. Genotyping was done by the TaqMan real-time polymerase chain...
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