Article
Frequency of CD4(+)CD25(hi)FOXP3(+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Jul 2010
Magenau John M, Qin Xuemei, Tawara Isao, Rogers Clare E, Kitko Carrie, Schlough Matthew, Bickley Daniel, Braun Thomas M, Jang Pil-Sang, Lowler Kathleen P, Jones Dawn M, Choi Sung W, Reddy Pavan, Mineishi Shin, Levine John E, Ferrara James L M, Paczesny Sophie
Abstract excerpt
The relationship between regulatory T cells (Tregs) and acute graft-versus-host disease (aGVHD) in clinical allogeneic bone marrow transplantation (BMT) recipients is not well established. We conducted a prospective analysis of peripheral blood Tregs as determined by the frequency of CD4(+)CD25(h...
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