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Article

Marker-less deletion of cctA gene of Clostridium chauvoei.

Anaerobe - 1 Feb 2020

Gupta Sanjay Kumar, Dixit Sameer, Dangi Saroj K, Kaur Gurpreet, Mashooq Mohmad, Karthik Kumaragurubaran, Sarkar Mihir, Mahajan Sonalika, Nagaleekar Viswas Konasagara

Abstract excerpt

Clostridium chauvoei causes blackleg disease in domestic animals, especially cattle and sheep. The pathogen produces several toxins including CctA - a hemolysin and protective antigen. Molecular pathogenesis of the disease is poorly understood, possibly due to lack of genetic manipulation tools for C. chauvoei. In the present study, we report the marker-less deletion of cctA gene using the CRISPR-Cas9 system. The...

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Identifiers

PMID: 31711886
DOI: 10.1016/j.anaerobe.2019.102116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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