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Article

Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs.

Atherosclerosis - 1 Dec 2019

Lorenz Mario, Blaschke Benjamin, Benn Andreas, Hammer Elke, Witt Eric, Kirwan Jennifer, Fritsche-Guenther Raphaela, Gloaguen Yoann, Bartsch Cornelia, Vietzke Angelika, Kramer Frederike, Kappert Kai, Brunner Patrizia, Nguyen Hoang Giang, Dreger Henryk, Stangl Karl, Knaus Petra, Stangl Verena

Abstract excerpt

BACKGROUND AND AIMS: Gonadal hormones are mainly thought to account for sex and gender differences in the incidence, clinical manifestation and therapy of many cardiovascular diseases. However, intrinsic sex differences at the cellular level are mostly overlooked. Here, we assessed sex-specific metabolic and functional differences between male and female human umbilical vein endothelial cells (HUVECs). METHODS:...

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Identifiers

PMID: 31706078
DOI: 10.1016/j.atherosclerosis.2019.10.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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