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Human umbilical endothelial cells (HUVECs) have a sex: characterisation of the phenotype of male and female cells

1 Dec 2014

Abstract excerpt

BACKGROUND: Human umbilical endothelial cells (HUVECs) are widely used to study the endothelial physiology and pathology that might be involved in sex and gender differences detected at the cardiovascular level. This study evaluated whether HUVECs are sexually dimorphic in their morphological, proliferative and migratory properties and in the gene and protein expression of oestrogen and androgen receptors and...

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PMID: 25535548
DOI: 10.1186/s13293-014-0018-2

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