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Article

Sex-specific effects of leptin administration to pregnant mice on the placentae and the metabolic phenotypes of offspring.

FEBS open bio - 1 Jan 2020

Denisova Elena I, Kozhevnikova Valeria V, Bazhan Nadezhda M, Makarova Elena N

Abstract excerpt

Obesity during pregnancy has been shown to increase the risk of metabolic diseases in the offspring. However, the factors within the maternal milieu which affect offspring phenotypes and the underlying mechanisms remain unknown. The adipocyte hormone leptin plays a key role in regulating energy homeostasis and is known to participate in sex-specific developmental programming. To examine the action of leptin on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31703240
DOI: 10.1002/2211-5463.12757
PMCID: PMC6943234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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