Article
[Sequence analysis and 3D molecular structure simulation of a novel HLA allele B*51:159].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Nov 2019
Qiao Wenben, Song Yonghong, Nie Xiangmin, Liu Yan, Zhu Haifeng, Zhang Yi
Abstract excerpt
OBJECTIVE: To identify a novel human leukocyte antigen (HLA) B allele in a Chinese Han individual and construct its three-dimensional structure. METHODS: The initial HLA genotyping was performed by PCR-sequence-based typing (PCR-SBT). The ambiguous allele was confirmed with single-strand DNA sequencing. The DNA sequence was analyzed to identify the difference between the novel allele and its closest matching...
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