[Identification and sequence analysis of a novel HLA-A * 3018 allele].

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[Identification and sequence analysis of a novel HLA-A * 3018 allele].

Zhongguo shi yan xue ye xue za zhi - 1 Oct 2007

Li Zhen, Zou Hong-Yan, Shao Chao-Peng, Sun Ge, Jin Shi-Zheng, Cheng Liang-Hong

Abstract excerpt

To identify HLA novel allele in Chinese Han individuals, an unknown HLA-A allele was detected by PCR-SSP and FLOW-SSO in Chinese Han individuals. Heterozygous sequence-based typing (SBT) showed that there were 3 differences compared with database in exon 2. Its anomalous patterns suggested the possible presence of either a novel A * 30 or a novel A * 24. To separate the two alleles and to determine whether the...

Topics

Alleles
Amino Acid Sequence
Asian People
Base Sequence
China
HLA-A Antigens
Humans
Molecular Sequence Data
Sequence Analysis, DNA

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Open in PubMed

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PMID: 17956698

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