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Article

Genomic analysis of a Chinese MDV strain derived from vaccine strain CVI988 through recombination.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2020

He Liangliang, Li Jie, Peng Peng, Nie Jingsong, Luo Jun, Cao Yongchang, Xue Chunyi

Abstract excerpt

Disease caused by Marek's disease virus (MDV), a highly oncogenic alpha-herpesvirus, is controlled mainly by vaccination. Since 1990s, CVI988 has been widely used as vaccine strain. However, as an attenuated live vaccine, CVI988 has the potential of virulence enhancement and the risk of recombination that should be considered. In this study, we sequenced the whole genome of a Chinese strain HNLC503 and found the...

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PMID: 31698116
DOI: 10.1016/j.meegid.2019.104045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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