Article
Recombination with a vaccine strain drives the evolution of a more virulent phenotype in avian infectious bronchitis virus.
Poultry science - 1 Jun 2026
Huang Zhonglin, Wang Xu, Ren Hongfeng, Li Pei, Wang Yang, Zhao Yafan, Guo Jinchi, Chen Yingjie, Wang Pengran, Li Xiaoran, Guo Yanna, Li Jianhui, Liang Libin, Li Junping
Abstract excerpt
Avian infectious bronchitis virus (IBV), a major pathogen in the poultry industry, evolves rapidly via genetic mutations and recombination. While recombination between field and live vaccine strains is well-documented, its direct role in viral virulence remains unclear. In this study, four novel IBV field strains (SX/2407, SX/2408, SX/2409, SX/2410) were isolated from a single layer farm in Shanxi Province,...
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