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Genetic recombination in fast-spreading coxsackievirus A6 variants: a potential role in evolution and pathogenicity

30 Jun 2020

Abstract excerpt

Abstract Hand, foot, and mouth disease (HFMD) is a common global epidemic. From 2008 onwards, many HFMD outbreaks caused by coxsackievirus A6 (CV-A6) have been reported worldwide. Since 2013, with a dramatically increasing number of CV-A6-related HFMD cases, CV-A6 has become the predominant HFMD pathogen in mainland China. Phylogenetic analysis based on the VP1 capsid gene revealed that subtype D3 dominated the...

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PMID: 34804589
DOI: 10.1093/ve/veaa048

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