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Article

A novel subgenotype C6 Enterovirus A71 originating from the recombination between subgenotypes C4 and C2 strains in mainland China.

Scientific reports - 12 Jan 2022

Liu Yongjuan, Zhou Jingyi, Ji Guangquan, Gao Yupeng, Zhang Chunyan, Zhang Ting, Huo Juan, Liang Wenxue, Yang Jin, Shi Yingying, Zhao Shaolin

Abstract excerpt

Recombination plays important roles in the genetic diversity and evolution of Enterovirus A71 (EV-A71). The phylogenetics of EV-A71 in mainland China found that one strain DL71 formed a new subgenotype C6 with unknown origin. This study investigated the detailed genetic characteristics of the new variant. DL71 formed a distinct cluster within genotype C based on the genome and individual genes (5'UTR, VP4, VP1,...

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Identifiers

PMID: 35022489
DOI: 10.1038/s41598-021-04604-x
PMCID: PMC8755819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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