Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aproximación genética en la esclerosis lateral amiotrófica.

Gaceta medica de Mexico - 1 Jan 2019

Cervantes-Aragón Iván, Ramírez-García Sergio Alberto, Baltazar-Rodríguez Luz Margarita, García-Cruz Diana, Castañeda-Cisneros Gema

Abstract excerpt

The superoxide dismutase type 1 (SOD1) gene is the first responsible gene mapped in amyotrophic lateral sclerosis type 1 (ALS1), and it codes for the enzyme SOD1, the function of which is to protect against damage mediated by free radicals deriving from oxygen. Its pathophysiological mechanism in ALS1 is related to ischemia. Several molecular studies of the SOD1 gene show that point mutations are the most...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to C9orf72 Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Helicases

Share to Ischemia

Share to Multifunctional Enzymes

Share to Reactive Oxygen Species

Share to RNA Helicases

Share to Superoxide Dismutase-1

Source

Identifiers

PMID: 31695223
DOI: 10.24875/GMM.19004927

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aproximación genética en la esclerosis lateral amiotrófica.PMID 31695223Read ↗

Clinical and molecular features of patients with amyotrophic lateral sclerosis and SOD1 mutations: a monocentric studySemantic proximity Read ↗

Individual Oligogenic Background in p.D91A-SOD1 Amyotrophic Lateral Sclerosis Patients.Semantic proximity Read ↗

[Attention should be paid to the importance of genetic testing in clinical practice of amyotrophic lateral sclerosis].Semantic proximity Read ↗

Clinical and Molecular Landscape of ALS Patients with SOD1 Mutations: Novel Pathogenic Variants and Novel Phenotypes. A Single ALS Center Study.Semantic proximity Read ↗

Heterozygous D90A-SOD1 mutation in an Italian ALS patient with atypical presentation.Semantic proximity Read ↗

Unveiling the SOD1-mediated ALS phenotype: insights from a comprehensive meta-analysis.Semantic proximity Read ↗

Evidence for an oligogenic basis of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Oxidative Stress in Amyotrophic Lateral Sclerosis: Synergy of Genetic and Environmental FactorsSemantic proximity Read ↗

Impact of a frequent nearsplice SOD1 variant in amyotrophic lateral sclerosis: optimising SOD1 genetic screening for gene therapy opportunities.Semantic proximity Read ↗

A novel SOD1 gene mutation in a Korean family with amyotrophic lateral sclerosis.Semantic proximity Read ↗

Molecular genetic basis of familial ALS.Semantic proximity Read ↗

No association of GSTP1 rs1695 polymorphism with amyotrophic lateral sclerosis: A case-control study in the Brazilian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.