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Article

Insights into wild-type dynamin 2 and the consequences of DNM2 mutations from transgenic zebrafish.

Human molecular genetics - 15 Dec 2019

Zhao Mo, Smith Lindsay, Volpatti Jonathan, Fabian Lacramioara, Dowling James J

Abstract excerpt

Dynamin 2 (DNM2) encodes a ubiquitously expressed large GTPase with membrane fission capabilities that participates in the endocytosis of clathrin-coated vesicles. Heterozygous mutations in DNM2 are associated with two distinct neuromuscular disorders, Charcot-Marie-Tooth disease (CMT) and autosomal dominant centronuclear myopathy (CNM). Despite extensive investigations in cell culture, the role of dynamin 2 in...

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Source

Identifiers

PMID: 31691805
DOI: 10.1093/hmg/ddz260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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